Alcohol Dehydrogenases as Tools for the Preparation of Enantiopure Metabolites of Drugs with Methyl Alkyl Ketone Moiety

Application of Water for Synthesis of Cyclopentadienes via Multi-component Reactions of N-methyl imidazole

A water-accelerated multi-component synthesis of organic target molecules was used as a key method for the preparation of cyclopentadiene derivatives. The three-component condensation reactions of primary amines with alkyl propiolates in the presence of N-methylimidazole in water at room temperature were developed as efficient and clean green synthetic procedures for the high-yielding preparati...

NITROIMIDAZOLES IV [I]. SYNTHESIS OF 3,s-DICARBO ALKOXY-2,6-DIMETHYL-4-(1 -METHYL-5- NITRO-2-1MIDAZOLYL)-1,4-DIHYDROPYRIDIANNE D 3,5-DICARBOALKOXY- 2,6-DIMETHYL-4(-2 -S UBSTI - TUTED-4-THIAZOLYL)-l , 4- DIHYDROPYRIDINE

Different procedures for the syntheses of the title compounds were investigated. The best method for the preparation of the title compounds were the reaction of the readily available 2-formyL-1-methyl-5-nitroimidazole2- substituted-4-formylthiazoles with alkyl acetoacetate and alkyl aminocrotonate in boiling alcohol.

Abatement of Benzyl Alcohol and Methyl Ethyl Ketone (MEK) from Polluted Air Over Nanostructured Mn -Supported Alumina Catalyst

Promiscuous Substrate-Binding Explains the Enzymatic Stereo- and Regiocontrolled Synthesis of Enantiopure Hydroxy Ketones and Diols

Regioand stereoselective reductions of several diketones to afford enantiopure hydroxy ketones or diols were accomplished using isolated alcohol dehydrogenases (ADHs). Results could be rationalised taking into account different (promiscuous) substrate-binding modes in the active site of the enzyme. Furthermore, interesting natural cyclic diketones were also reduced with high regioand stereosele...

Separation of methacrylic acid from aqueous phase using quaternary amine

The feasibility of extractive reaction of methacrylic acid from aqueous solution using a quaternary amine, tri–octyl methyl ammonium chloride (TOMAC) as an extractant, was studied. The diluents chosen in the present work belong to different chemical classes, n–butyl acetate, carbon tetrachloride, isoamyl alcohol, methyl isobutyl ketone, and toluene. The effect of initial acid concentration in t...